CR1L anticorps

N° du produit ABIN782451

Cet anticorps anti-CR1L est un anticorps Souris Monoclonal détectant CR1L dans IHC (fro) et FACS. Adapté pour Rat.

Aperçu rapide pour CR1L anticorps (ABIN782451)

Antigène: CR1L (Complement Component (3b/4b) Receptor 1-Like (CR1L))

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CR1L est non-conjugé

Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)

Clone: 512

Détail du produit anti-CR1L anticorps

Specificité: Purified Anti-Rat Crry monoclonal antibody (Clone: 5I2) is a rat-specific membrane complement regulator that can inhibit both antibody-induced classical pathway and alternative pathway complement activation. Crry plays a more dominant role than DAF in regulating the alternative pathway of complement and in preventing spontaneous complement damage of rat erythrocytes, whereas DAF and Crry are both expressed and are equally effective in preventing antibody-induced runaway complement activation on rat erythrocytes.

Purification: Affinity chromatography on Protein G

Immunogène: Erythrocytes from a C3 mutated rat

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: PBS containing 0.02 % sodium azide (NaN3) as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CR1L

Antigène: CR1L (Complement Component (3b/4b) Receptor 1-Like (CR1L))

Autre désignation: CR1L / CRRY

Sujet: Synonyms: Antigen 5I2, Complement component receptor 1-like protein, Complement regulatory protein Crry

ID gène: 54243

NCBI Accession: NP_001005265

UniProt: Q63135

Pathways: Système du Complément